Learn more
about
Along with diet and exercise, JENTADUETO:
Can help lower
your A1C
Can help your body
produce more insulin
and less sugar
Offers Twice-daily dosing
Even when you're doing everything you can to eat well and get enough physical activity, your numbers may not be going in the direction you and your doctor want them to. But there are ways to help, and you don't have to do it on your own.
JENTADUETO is a twice-daily pill that, when used along with diet and exercise, can help lower blood sugar in adults with type 2 diabetes. It's a combination prescription medication that contains two diabetes medicines, linagliptin and metformin.
JENTADUETO is not for people with type 1 diabetes. If you have had inflammation of the pancreas (pancreatitis) in the past, it is not known if you have a higher chance of getting pancreatitis while you take JENTADUETO.
JENTADUETO belongs to two classes of drugs: DPP-4 inhibitors and biguanides. DPP-4 inhibitors work by increasing hormones that stimulate your pancreas to produce more insulin and stimulate your liver to produce less glucose. Biguanides work by reducing the amount of glucose in your blood and by increasing insulin sensitivity.
The two medicines together, along with diet and exercise, can help your body produce more insulin, and less sugar. Managing your sugar can mean a lower A1C – and that's an important goal for anyone with type 2 diabetes.
Take JENTADUETO exactly as your doctor tells you to take it.
Take JENTADUETO two times each day with meals to lower your chance of stomach upset.
If you miss a dose, take it with a meal when you remember, or skip it until your next scheduled dose.
Symptoms of an allergic reaction may include rash, itching, flaking or peeling of your skin; raised red patches on your skin (hives); and swelling of your face, lips, tongue and throat that may cause difficulty breathing or swallowing. If you have any symptoms of a serious allergic reaction, stop taking JENTADUETO and call your doctor or go to the emergency room right away.
JENTADUETO and JENTADUETO XR are prescription medicines that contain 2 diabetes medicines, linagliptin (TRADJENTA) and metformin hydrochloride. JENTADUETO and JENTADUETO XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
JENTADUETO and JENTADUETO XR are not for people with type 1 diabetes. If you have had inflammation of the pancreas (pancreatitis) in the past, it is not known if you have a higher chance of getting pancreatitis while you take JENTADUETO or JENTADUETO XR.
JENTADUETO and JENTADUETO XR can cause serious side effects, including Lactic Acidosis (a build-up of lactic acid in the blood). Metformin, one of the medicines in JENTADUETO and JENTADUETO XR, can cause lactic acidosis, a rare but serious condition that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.
Stop taking JENTADUETO or JENTADUETO XR and call your healthcare provider right away or go to the nearest hospital emergency room if you get any of the following symptoms, which could be signs of lactic acidosis: feel very weak and tired, have unusual muscle pain, have trouble breathing, have stomach or intestinal problems with nausea and vomiting, or diarrhea, feel sleepy or sleep longer than usual, feel cold in your arms and legs, feel dizzy or lightheaded, or have a slow or irregular heartbeat.
You have a higher chance of getting lactic acidosis with JENTADUETO or JENTADUETO XR if you have severe kidney problems, liver problems, drink a lot of alcohol (very often or short-term "binge" drinking), get dehydrated (lose a large amount of body fluids), have x-ray tests with injectable dye, have surgery, have congestive heart failure, have a heart attack, severe infection, or stroke, or are 65 years of age or older.
Inflammation of the pancreas (pancreatitis) is another serious side effect that can happen to people taking JENTADUETO or JENTADUETO XR. Pancreatitis may be severe and lead to death. Before you start taking JENTADUETO or JENTADUETO XR tell your healthcare provider if you have ever had pancreatitis, gallstones, a history of alcoholism, or high triglyceride levels.
Stop taking JENTADUETO or JENTADUETO XR and call your healthcare provider right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.
Do not take JENTADUETO or JENTADUETO XR if you:
Tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. JENTADUETO or JENTADUETO XR may affect the way other medicines work, and other medicines may affect how JENTADUETO or JENTADUETO XR works.
Especially tell your healthcare provider if you take:
JENTADUETO and JENTADUETO XR may cause serious side effects, including:
The most common side effects of JENTADUETO and JENTADUETO XR include stuffy or runny nose, sore throat, and diarrhea.
These are not all the possible side effects of JENTADUETO and JENTADUETO XR. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑10881‑800‑FDA‑1088.
CL-JD-100033 4.22.2022
Please see Prescribing Information, including Boxed Warning about lactic acidosis, and Medication Guide for JENTADUETO.
Please see Prescribing Information, including Boxed Warning about lactic acidosis, and Medication Guide for JENTADUETO XR.
JENTADUETO and JENTADUETO XR are prescription medicines that contain 2 diabetes medicines, linagliptin (TRADJENTA) and metformin hydrochloride. JENTADUETO and JENTADUETO XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
JENTADUETO and JENTADUETO XR are not for people with type 1 diabetes. If you have had inflammation of the pancreas (pancreatitis) in the past, it is not known if you have a higher chance of getting pancreatitis while you take JENTADUETO or JENTADUETO XR.
JENTADUETO and JENTADUETO XR can cause serious side effects, including Lactic Acidosis (a build-up of lactic acid in the blood). Metformin, one of the medicines in JENTADUETO and JENTADUETO XR, can cause lactic acidosis, a rare but serious condition that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.
Stop taking JENTADUETO or JENTADUETO XR and call your healthcare provider right away or go to the nearest hospital emergency room if you get any of the following symptoms, which could be signs of lactic acidosis: feel very weak and tired, have unusual muscle pain, have trouble breathing, have stomach or intestinal problems with nausea and vomiting, or diarrhea, feel sleepy or sleep longer than usual, feel cold in your arms and legs, feel dizzy or lightheaded, or have a slow or irregular heartbeat.
You have a higher chance of getting lactic acidosis with JENTADUETO or JENTADUETO XR if you have severe kidney problems, liver problems, drink a lot of alcohol (very often or short-term "binge" drinking), get dehydrated (lose a large amount of body fluids), have x-ray tests with injectable dye, have surgery, have congestive heart failure, have a heart attack, severe infection, or stroke, or are 65 years of age or older.
Inflammation of the pancreas (pancreatitis) is another serious side effect that can happen to people taking JENTADUETO or JENTADUETO XR. Pancreatitis may be severe and lead to death. Before you start taking JENTADUETO or JENTADUETO XR tell your healthcare provider if you have ever had pancreatitis, gallstones, a history of alcoholism, or high triglyceride levels.
Stop taking JENTADUETO or JENTADUETO XR and call your healthcare provider right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.
Do not take JENTADUETO or JENTADUETO XR if you:
Tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. JENTADUETO or JENTADUETO XR may affect the way other medicines work, and other medicines may affect how JENTADUETO or JENTADUETO XR works.
Especially tell your healthcare provider if you take:
JENTADUETO and JENTADUETO XR may cause serious side effects, including:
The most common side effects of JENTADUETO and JENTADUETO XR include stuffy or runny nose, sore throat, and diarrhea.
These are not all the possible side effects of JENTADUETO and JENTADUETO XR. For more information, ask your healthcare provider or pharmacist.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑10881‑800‑FDA‑1088.
CL-JD-100033 4.22.2022
Please see Prescribing Information, including Boxed Warning about lactic acidosis, and Medication Guide for JENTADUETO.
Please see Prescribing Information, including Boxed Warning about lactic acidosis, and Medication Guide for JENTADUETO XR.
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